Electrochemical Detection of Bisphenol A by Tyrosinase Immobilized on Electrospun Nanofibers Decorated with Gold Nanoparticles

Bisphenol A (BPA) is an endocrine-disrupting chemical (EDC) employed in industrial processes that causes adverse effects on the environment and human health. Sensitive inexpensive methods to detect BPA are therefore needed. In this paper, we describe electrochemical biosensor for detecting low levels of using polymeric electrospun nanofibers polyamide 6 (PA6) poly(allylamine hydrochloride) (PAH) decorated with gold nanoparticles (AuNPs), namely, PA6/PAH@AuNPs, which were deposited onto a fluorine-doped tin oxide (FTO) substrate. The hybrid layer was excellent immobilization tyrosinase (Tyr), allowed amperometric detection limit 0.011 ?M concentration range from 0.05 20 ?M. Detection also possible real water samples recoveries 92–105%. improved sensing performance attributed combined effect large surface area porosity PA6/PAH nanofibers, catalytic activity AuNPs, oxidoreductase ability Tyr. These results provide route novel biosensing architectures monitor other EDCs resources.